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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10856 | Cobimetinib (R-enantiomer) | XL-518 R-enantiomer,Cobimetinib R-enantiomer,GDC-0973 R-enantiomer | Others |
Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib which is a selective MEK inhibitor. | |||
T22677 | Cobimetinib racemate | Cobimetinib (racemate) | MEK |
Cobimetinib racemate (Cobimetinib (racemate)) (GDC-0973 racemate) is a selective inhibitor of MEK.Cobimetinib racemate is also known as a mitogen-activated protein kinase, is a key component of the RAS/RAF/MEK/ERK pathwa... | |||
T64175 | Cobimetinib hemifumarate | ||
Cobimetinib hemifumarate is a potent and selective MEK1 inhibitor with an IC50 value of 4.2 nM for MEK1. | |||
T3623 | Cobimetinib | RG7420,XL518,GDC-0973 | Apoptosis , MEK |
Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of e... |